AECOM has filed a patent for methods, devices, and systems for ultra-high dose radiotherapy. The patent describes the use of active switching control of a photoconductive switch in a particle accelerator to produce output radiation at desired dose rates. The method involves receiving a charged particle beam, producing voltage pulses through the photoconductive switch in response to light, and accelerating the charged particles to produce output radiation beams for flash radiotherapy. GlobalData’s report on AECOM gives a 360-degree view of the company including its patenting strategy. Buy the report here.
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According to GlobalData’s company profile on AECOM, Forward inferencing was a key innovation area identified from patents. AECOM's grant share as of September 2023 was 56%. Grant share is based on the ratio of number of grants to total number of patents.
Ultra-high dose radiotherapy using active switching control of photoconductive switch
A recently filed patent (Publication Number: US20230310897A1) describes a method for producing output radiation in a flash radiotherapy system. The method involves receiving a charged particle beam from a particle source at a particle accelerator system, which includes a photoconductive switch. The photoconductive switch, operating in a linear mode, is made of a doped crystalline material that can establish an electric field when voltage is applied.
In this method, the photoconductive switch produces voltage pulses in response to incident light on the crystalline material. These voltage pulses are then used to accelerate the charged particles in the particle accelerator, resulting in the production of one or more output radiation beams for flash radiotherapy.
The patent also includes additional claims for modifying the output radiation beams. One claim involves measuring the output radiation beams and adjusting the voltage pulses supplied to the particle accelerator based on the measurements. Another claim describes producing output radiation beams with specific dose rates and irradiating the entire target region with these dose rates.
The method also allows for modifying the energy, dose rate, or average dose rate of the output radiation beams based on the voltage pulses produced by the photoconductive switch. The voltage pulses can have non-Gaussian or top hat profiles, and the charged particles can be electrons. The particle accelerator system can be an induction linear accelerator, and the method can involve operating light sources, such as laser light sources, to produce the light received by the photoconductive switch.
The voltage source used to establish the electric field can range from 10 kV to 100 kV, and the method can accommodate multiple charged particle beams. The patent also claims the ability to control the dose rate provided by the output radiation beams and irradiate patients using these beams. The output radiation beams can be in the form of a series of pulses, and the characteristics of the beams can be modified by adjusting the voltage pulses produced by the photoconductive switch. The response time of the switch is in the range of 1 ns to 10 ns, and the energy source can include one or more capacitors.
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